Fetal distress, interventions and newborn outcomes at a National Referral Hospital in Kampala Uganda: A retrospective study

Authors

  • Elizabeth Ayebare Department of Nursing, School of Health Sciences, College of Health Sciences, Makerere University, Uganda Author
  • Rose C. Nabirye Department of Nursing, Faculty of Health Sciences, Busitema University, Uganda Author
  • Grace Ndeezi Department of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Uganda Author
  • Allen Nabisere Department of Health Policy Planning and Management, School of Public Health, College of Health Sciences, Makerere University, Uganda Author
  • Musa Sekikuubo Department of Obstetrics and Gynaecology, School of Medicine, College of Health Sciences, Makerere University, Uganda Author
  • James K. Tumwine Department of Paediatrics and Child Health, Faculty of Medicine, Kabale University, Uganda Author
  • Jolly Nankunda Mulago Specialized Women’s & Neonatal Hospital, Kampala, Uganda Author

Keywords:

Apgar score, fetal hypoxia, newborn, fetal heart rate, Uganda

Abstract

Background:

Fetal distress, also known as non-reassuring fetal status, is a major contributor to poor newborn outcomes before and after birth. This study examined the clinical diagnosis of fetal distress and the newborn outcomes in a three-month cohort of women. 

Methods:

This was a retrospective cohort study where 5404 maternity case records of women who gave birth at Kawempe National Referral Hospital during June to August 2019 were reviewed. Data were collected by trained nurse/midwives from the records using a checklist designed in Kobo Collect software. The data were exported to Stata 14 for cleaning and analysis. The prevalence of fetal distress was calculated as a percentage of those with a diagnosis out of the total number of records. All other data were summarized descriptively, and chi-square tests were computed to assess the association between fetal distress and newborn outcomes. 

Results:

The prevalence of fetal distress was 257/4799 (5.4%), and of these, 51.3% had an abnormal fetal heart rate < 120b/min or > 160b/min.  Meconium-stained amniotic fluid was present in 65% of all women diagnosed with fetal distress.  Interventions for fetal distress during labour were mainly: administration of intravenous fluids (28.8%), monitoring of the fetal heart rate (10.5%), and lateral positioning (4.3%). An emergency cesarean section was the most common mode of birth planned for women with fetal distress (90.7%), although eventually, only 76.7% delivered by cesarean section. Women with fetal distress were more likely (12.5%, p<0.001) to have newborns with low Apgar scores <7 at 5 minutes.

Conclusion:

Fetal distress occurred in 5.4% of case records reviewed, with the majority undergoing a cesarean section birth. Despite the interventions such as intravenous fluid infusion, FHR monitoring, and lateral positioning, poor outcomes were observed more in those with fetal distress than in those without.

References

1. ACOG Committee Opinion #326: Inappropriate Use of the Terms Fetal Distress and Birth Asphyxia. (2005). Obstetrics and Gynecology (New York, 1953), 106(6), 1469-1470. https://doi.org/10.1097/00006250-200512000-00056

2. Adhikari, S., & Rao, K. S. (2017). Neurodevelopmental outcome of term infants with perinatal asphyxia with hypoxic ischemic encephalopathy stage II. Brain and Development, 39(2), 107-111. https://doi.org/10.1016/j.braindev.2016.09.005

3. Akhter, A., Begum, A., Sultana, N., Saha, S., Chowdhury, M. N., & Saifullah, A. N. M. (2021). Early Neonatal Outcome of Clinically Diagnosed Fetal Distress in Low-Resource Areas. Medicine Today, 33(2), 152-155. https://doi.org/10.3329/medtoday.v33i2.56063

4. Ayebare, E., Jonas, W., Ndeezi, G., Nankunda, J., Hanson, C., Tumwine, J. K., & Hjelmstedt, A. (2020). Fetal heart rate monitoring practices at a public hospital in Northern Uganda - what health workers document, do, and say. Glob Health Action, 13(1), 1711618. https://doi.org/10.1080/16549716.2020.171161

5. Belete, E., Bazezew, Y., Desta, M., Misganaw, D., & Tefera, M. (2022). Magnitude, Associated Factors and Immediate Outcomes of Non-Reassuring Fetal Heart Rate Status Among Laboring Mothers at South Gondar Zone Public Hospitals, North, West Ethiopia, 2022 Cross-sectional Study. medRxiv, 2022.2010.2002.22280615. https://doi.org/10.1101/2022.10.02.22280615

6. Betran, A. P., Ye, J., Moller, A. B., Souza, J. P., & Zhang, J. (2021). Trends and projections of caesarean section rates: global and regional estimates. BMJ Glob Health, 6(6). https://doi.org/10.1136/bmjgh-2021-005671

7. Briozzo, L., Martinez, A., Nozar, M., Fiol, V., Pons, J., & Alonso, J. (2007). Tocolysis and delayed delivery versus emergency delivery in cases of non‐reassuring fetal status during labor. Journal of Obstetrics and Gynaecology Research, 33(3), 266-273. https://doi.org/10.1111/j.1447-0756.2007.00522.x

8. Bullens, L. M., van Runnard Heimel, P. J., van der Hout-van der Jagt, M. B., & Oei, S. G. (2015). Interventions for Intrauterine Resuscitation in Suspected Fetal Distress During Term Labor: A Systematic Review. Obstetrical & Gynecological Survey, 70(8), 524-539. https://doi.org/10.1097/OGX.0000000000000215

9. Bullens, L. M., van Runnard Heimel, P. J., van der Hout-van, M. B., & Oei, S. G. (2015). Interventions for intrauterine resuscitation in suspected fetal distress during term labor: a systematic review. Obstetrical & Gynecological Survey, 70(8), 524-539. https://doi.org/10.1097/OGX.0000000000000215

10. Byaruhanga, R., Bassani, D. G., Jagau, A., Muwanguzi, P., Montgomery, A. L., & Lawn, J. E. (2015). Use of wind-up fetal Doppler versus Pinard for fetal heart rate intermittent monitoring in labour: a randomised clinical trial. BMJ open, 5(1), e006867. https://doi.org/10.1136/bmjopen-2014-006867

11. De Souza, S. W., John, R. W., Richards, B., & Milner, R. D. (1975). Fetal distress and birth scores in newborn infants. Arch Dis Child, 50(12), 920-926. https://doi.org/10.1136/adc.50.12.920

12. Gangwar, R., & Chaudhary, S. (2016). Caesarean Section for Foetal Distress and Correlation with Perinatal Outcome. J Obstet Gynaecol India, 66(Suppl 1), 177-180. https://doi.org/10.1007/s13224-015-0831-5

13. Garite, T. J., & Simpson, K. R. (2011). Intrauterine resuscitation during labor. Clinical obstetrics and gynecology, 54(1), 28-39. https://doi.org/10.1097/GRF.0b013e31820a062b

14. Golubnitschaja, O., Yeghiazaryan, K., Cebioglu, M., Morelli, M., & Herrera-Marschitz, M. (2011). Birth asphyxia as the major complication in newborns: moving towards improved individual outcomes by prediction, targeted prevention, and tailored medical care. EPMA Journal, 2(2), 197-210. https://doi.org/10.1007/s13167-011-0087-9

15. Hoque, M. (2011). Incidence of Obstetric and Foetal Complications during Labor and Delivery at a Community Health Centre, Midwives Obstetric Unit of Durban, South Africa. ISRN Obstetrics and Gynecology, 2011, 259308. https://doi.org/10.5402/2011/259308

16. Hughes, N. J., Namagembe, I., Nakimuli, A., Sekikubo, M., Moffett, A., Patient, C. J., & Aiken, C. E. (2020). Decision-to-delivery interval of emergency cesarean section in Uganda: a retrospective cohort study. BMC Pregnancy and Childbirth, 20(1), 324. https://doi.org/10.1186/s12884-020-03010-x

17. Kassahun, E. A., Aweke, A. M., Getu, A. A., Gela, G. B., Limenih, S. K., Mekonnen, M. E., & Abtie, T. A. (2020). Proportion and associated factors of nonreassuring fetal heart rate patterns in Finote Selam Primary Hospital, North West Ethiopia. Biomed Res Int, 2020. https://doi.org/10.1155/2020/6948972

18. Khanum, S., & Chowdhury, L. (2020). Justification of Cesarean section in fetal distress: Experience in a tertiary care military hospital in Bangladesh. BIRDEM Medical Journal, 10(1), 60-63.

19. https://doi.org/10.3329/birdem.v10i1.44762

20. Khumalo, M., Leonard, T., Scribante, J., & Perrie, H. (2022). A retrospective review of the decision to deliver the time interval for foetal distress at a Central Hospital. International journal of women's health, 1723-1732.

21. https://doi.org/10.2147/IJWH.S382518

22. Kobo Toolbox. Retrieved from https://www.kobotoolbox.org/

23. Litorp, H., Gurung, R., Målqvist, M., & Kc, A. (2020). Disclosing suboptimal indications for emergency caesarean sections due to fetal distress and prolonged labor: a multicenter cross-sectional study at 12 public hospitals in Nepal. Reproductive Health, 17(1), 197. https://doi.org/10.1186/s12978-020-01039-x

24. Mgaya, A. H., Litorp, H., Kidanto, H. L., Nyström, L., & Essén, B. (2016). Criteria-based audit to improve quality of care of foetal distress: standardising obstetric care at a national referral hospital in a low resource setting, Tanzania. BMC Pregnancy and Childbirth, 16(1), 343. https://doi.org/10.1186/s12884-016-1137-z

25. Ministry of Health. (2021). Why are Mothers and Babies still dying? What else needs to be done? The National FY 2020/2021 Annual Maternal and Perinatal Death Surveillance and Response (MPDSR) Report

26. Retrieved from Kampala, Uganda: Ministry of Health (Ed.) (2022). Essential Maternal and Newborn Clinical Care Guidelines for Uganda. Kampala, Uganda: Reproductive and Child Health Department

27. Namwaya, Z., Birungi, S., Namutebi, E., Ayebare, E., Namutebi, M., Muwanguzi, S., . . . Smyth, R. (2017). Partograph initiation and completion: a criteria-based audit study in Uganda. African Journal of Midwifery and Women's Health, 11(2), 72-76. https://doi.org/10.12968/ajmw.2017.11.2.72

28. Ogunkunle, T. O., Odiachi, H., Chuma, J. R., Bello, S. O., & Imam, A. (2020). Postnatal Outcomes and Risk Factors for In-Hospital Mortality among Asphyxiated Newborns in a Low-Resource Hospital Setting: Experience from North-Central Nigeria. Annals of Global Health. https://doi.org/10.5334/aogh.2884

29. Parer, J. T., & Livingston, E. G. (1990). What is fetal distress? Am J Obstet Gynecol, 162(6), 1421-1427. https://doi.org/10.1016/0002-9378(90)90901-I

30. Parween, S., Prasad, D., Poonam, P., Ahmar, R., Sinha, A., & Ranjana, R. (2022). Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital. Cureus, 14(4), e24464. https://doi.org/10.7759/cureus.24464

31. Rattanaprom, P., Ratinthorn, A., Sindhu, S., & Viwatwongkasem, C. (2023). Contributing factors of birth asphyxia in Thailand: a case-control study. BMC Pregnancy and Childbirth, 23(1), 584.

32. https://doi.org/10.1186/s12884-023-05885-y

33. Reddy, U. M., Weiner, S. J., Saade, G. R., Varner, M. W., Blackwell, S. C., Thorp, J. M., Jr.,... Caritis, S. N. (2021). Intrapartum Resuscitation Interventions for Category II Fetal Heart Rate Tracings and Improvement to Category I. Obstet Gynecol, 138(3), 409-416. https://doi.org/10.1097/AOG.0000000000004508

34. Rimsza, R., Stout, M. J., Kelly, J., Carter, E. B., Cahill, A. G., & Raghuraman, N. (2021). 670 Neonatal outcomes after cesarean for non-reassuring fetal status in the first stage of labor. American Journal of Obstetrics & Gynecology, 224(2), S421. https://doi.org/10.1016/j.ajog.2020.12.694

35. Roy, K. K., Baruah, J., Kumar, S., Deorari, A. K., Sharma, J. B., & Karmakar, D. (2008). Cesarean section for suspected fetal distress, continuous fetal heart monitoring, and decision to deliver at the right time. The Indian Journal of Pediatrics, 75(12), 1249-1252. https://doi.org/10.1007/s12098-008-0245-9

36. Simpson, K. R. (2007). Intrauterine Resuscitation During Labor: Review of Current Methods and Supportive Evidence. Journal of Midwifery & Women's Health, 52(3), 229-237. https://doi.org/10.1016/j.jmwh.2006.12.010

37. Unsworth, J., & Vause, S. (2010). Meconium in labour. Obstetrics, Gynaecology & Reproductive Medicine, 20(10), 289-294. https://doi.org/10.1016/j.ogrm.2010.06.005

38. Valencia, C. M., Escobar, M. F., Barona, J. S., Poblete, J. A., & Kusanovic, J. P. (2022). Intrauterine Fetal Resuscitation. In M. F. E. Vidarte (Ed.), The Continuous Textbook of Women's Medicine Series - Obstetrics Module. (Vol. Volume 13 Obstetric emergencies). Cali, Colombia: The Global Library of Women's Medicine. https://doi.org/10.3843/GLOWM.415083

39. Velayudhareddy, S., & Kirankumar, H. (2010). Management of foetal asphyxia by intrauterine foetal resuscitation. Indian J Anaesth, 54(5), 394-399. https://doi.org/10.4103/0019-5049.71032

Downloads

Published

2026-05-29

Issue

Section

Section of Clinical Nursing & Midwifery Practice

How to Cite

Fetal distress, interventions and newborn outcomes at a National Referral Hospital in Kampala Uganda: A retrospective study (E. Ayebare, R. C. Nabirye, G. Ndeezi, A. Nabisere, M. Sekikuubo, J. K. Tumwine, & J. Nankunda, Trans.). (2026). Uganda Journal of Nursing and Midwifery, 1(1). https://ujnm.org/index.php/public-html/article/view/1

Similar Articles

11-11 of 11

You may also start an advanced similarity search for this article.